Treatment of Intracranial Aneurysms with The Pipeline Embolization Device Only

Authors

  • V. Maus Department of Diagnostic and Interventional Neuroradiology, University Hospital Cologne, Cologne, Germany
  • A. Mpotsaris Department of Diagnostic and Interventional Neuroradiology, University Hospital Cologne, Cologne, Germany
  • J. Borggrefe Department of Diagnostic and Interventional Neuroradiology, University Hospital Cologne, Cologne, Germany
  • N. Abdullayev Department of Diagnostic and Interventional Neuroradiology, University Hospital Cologne, Cologne, Germany
  • T. Liebig Department of Neuroradiology, Charite, Berlin, Germany
  • F. Dorn Department of Neuroradiology, University Hospital Munich (LMU), Munich, Germany
  • P. Stavrinou Department of Neurosurgery, University Hospital Cologne, Cologne, Germany
  • G. Guliyeva Central Clinic Hospital, Baku, Azerbaijan
  • J. Mammadov Central Clinic Hospital, Baku, Azerbaijan
  • K. Ismayilova Center of Public Health and Reform, Baku, Azerbaijan
  • De-Hua Chang Department of Diagnostic and Interventional Neuroradiology, University Hospital Cologne, Cologne, Germany
  • C. Kabbasch Department of Diagnostic and Interventional Neuroradiology, University Hospital Cologne, Cologne, Germany

DOI:

https://doi.org/10.61788/njn.v1i21.07

Keywords:

intracranial aneurysms, flow diverter, pipeline embolization device, incomplete occlusion

Abstract

Currently, endovascular treatment of cerebral aneurysms is widespread. Purpose. The aim of this study was to evaluate the technical feasibility and rate of mid-term occlusion in aneurysms treated solely with the Pipeline Embolization Device (PED) in a German tertiary care university hospital. Materials and Methods. Forty-nine non-consecutive intracranial aneurysms underwent endovascular treatment using the PED exclusively between March 2011 and May 2017 at our institution. Primary endpoint was a favorable aneurysm occlusion defined as OKM C1-3 and D (O'Kelly Marotta Scale). Secondary endpoints were retreatment rate and delayed complications. Median follow-up was 200 days. Results. The mean aneurysm size was 7.1±5.3 mm. Forty-four aneurysms were located in the anterior circulation (90%). Ten aneurysms were ruptured (20%). Branching vessels from the sac were observed in 11 aneurysms (22%). Favorable obliteration immediately after PED placement was seen in 13/49 aneurysms (27%), of those nine aneurysms were completely occluded (18%). Angiographic and clinical follow-up was available for 45 cases (92%); 36/45 aneurysms (80%) were occluded completely and 40/45 aneurysms (89%) showed a favorable occlusion result. A branching vessel arising from the aneurysm sac was associated with incomplete occlusion (P<0.05). All electively treated patients had good outcome (mRS 0). Three aneurysms (6%) required additional treatment due to aneurysm recurrence. Conclusion. In our series, treatment of intracranial aneurysms with the PED was associated with favorable occlusion rates and low complication rates at mid-term follow-up. The presence of branching vessels arising from the aneurysms sac was predictive for an incomplete occlusion.

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Published

30.06.2021

How to Cite

Maus, V., Mpotsaris, A., Borggrefe, J., Abdullayev, N., Liebig, T., Dorn, F., … Kabbasch, C. (2021). Treatment of Intracranial Aneurysms with The Pipeline Embolization Device Only. National Journal of Neurology, 1(19), 45–54. https://doi.org/10.61788/njn.v1i21.07

Issue

2021: No.1 (19)

Section

Original Articles

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