Association of Single Nucleotide Polymorphism With Hypoxic-Ischemic Encephalopathy in Newborn
DOI:
https://doi.org/10.61788/njn.v2i26.03Keywords:
hypoxic-ischemic encephalopathy, newborns, gene, haplotype, single nucleotide polymorphism, sequencing of individual cells, apoptosisAbstract
The article presents the results of an analysis of literature data on the association of neonatal hypoxic-ischemic encephalopathy (HIE) with single-nucleotide polymorphism of individual genes and the frequency of gene haplotypes. Brief information is given on single nucleotide polymorphism (SNP), single cell sequencing (SCS) and the JAK-STAT signaling pathway. It is noted that the mechanisms explaining the association of single nucleotide polymorphism with HIE require further study, which will help to find new therapeutic targets.
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