Assesment of the Influence of Atoregenic Risk Factors on The Thickness of Intimamedia Complex of The Common Carotid Artery in Patients with Type 2 Diabetes Mellitus

Authors

  • R.K. Shiraliyeva Azerbaijan State Advanced Training Institute for Doctors named after A.Aliyev, Department of Neurology and Clinical Neurophysiology, Baku, Azerbaijan
  • N.K. Guliyeva Republican Clinical Hospital named after Acad. Mirgasimov, Department of Neurology, Baku, Azerbaijan
  • X.I. Hasanov Republican Clinical Hospital named after Acad. Mirgasimov, Department of Neurology, Baku, Azerbaijan
  • R.R. Aliyev Azerbaijan State Advanced Training Institute for Doctors named after A.Aliyev, Department of Neurology and Clinical Neurophysiology, Baku, Azerbaijan
  • D.M. Aliyeva Azerbajan Medical University, Deparment of Normal Physiology, Baku, Azerbaijan

DOI:

https://doi.org/10.61788/njn.v2i19.02

Keywords:

diabetes mellitus, arterial hipertension, intima-media complex, risk factors

Abstract

60 patients (26 male and 34 female) with type 2 diabetes mellitus at the average age of 58±15.2 years have been examined with the aim of studyng the influence of different atherogenic risk factors (hiperglicemia, hiperlipidemia, arterial hipertenzion (AH), smoking) on the thickness of intima-media complex (IMC) of common carotid arteries. The average duration of type 2 diabetes mellitus was 9.8±7.4 years and AH was 15.6±4.9 years. All patients underwent hospital for physical examination, evaluation of risk factors by electrocardiography, duplex scanning of extra cranial vessels, and etc. We evaluated the level of glicemia fasting in dynamics, of postprandial glicemia, indices of lipid spectrum. The obtained results showed that the ultrasound examination of the thickness of IMC made it possible to evaluate the negative influence of different atherogenic risk factors (mechanical – AH; biochemical – dyslipidemia, hipergicemia; toxic – smoking) on the condition of the arterial wall in patients with type 2 diabetes mellitus. In future it may faciliate to proper carrying out of active measures of prophylaxis of atherosclerosis, which would allow to hold up the development of the disease considerably and to reduce the frequency ofvascular complications.

References

Аносова Е.В. Прощаев К.И., Бессарабов В.И. и др. Определение сосудистого возрaста по толщине комплекса интима-медиа общих сонных артерии как метод выявления пациентов с ускаренными вариантами старения // Крооб. та гемостаз, 2012; № 12-с.150-152.

Абдуллаев. Р.Я., Калашников В.Й., Марченко В.Г. и др. Доплерография магистральных сосудов шеи. -Харьков-2008. 52 с.

Абдуллаев.Р.Я., Марченко В.Г., Дзяк Л.А. и др. Ультрасонография в неврологии. Харьков: Новое слово 2010. 152 с.

Пирагова Е.А. Ассосиация массы тела со смертностю у взрослых пациетов с сахарном диабетом // Ожирение и метаболизм, 2012; №4. -с.54.

Диагностика и лечение артериальной гипертонии. Клинические рекомендации. - Москва, 2013.-URL:htp: //www.s.cardio.ru.// Content (Guidclines). Eschiper-tenzion. 2013.pdf.

Диагностика и коррекция нарушений липидного обмена с целью профилактики и лечения атеросклероза. Российские рекомендации. Ѵ переосмотр. - Москва, - 2012. URL:htp:www. Scardio.ru.//content/ Guidelines/ rek-lipid-2012.pdf.

Дедова Л.В. Клиническое значение ультразвуковых допплеровских методов исследования у больных атеросклерозом различных сосудистых бассейнов и сахарным диабетом 2 типа: дис...д-ра мед. наук. - Москва, 2008. 232 с.

Aytekin E.R., Demir İ., Başarıcı İ., et al. Karotis intima-media kalınlıgının angiografik koronar arter hastalıgı varlıgı və yaylınlıgı ilə ilişgisi // Türk Kardiyal Arş. 2007, 35 (2): 90-6.

Bonetti P.O., Lerman L.O., Lerman A. Endothelial dysfunction: a marker of atherosclerotik risk // Arteroscler. Tromb Vase Biol -2003, -vol. 23-p.168-175.

Davignon J.,Gam P. Role of endothelial dysfunction: a marker in atherosclerosis // Circulation- 2004, -v0l 109.(suppl:1) – ІІІ 27- ІІІ 32.

Ronan R., Andrea N., Beverley B., Kurt H., Gabriel S., et all. Beta-cell funktion is associated with carotid intima-media thicknees independently of insulin resistance in healthy indivuduals // Journale of Hipertension, 2016, 34, 685-691.

Lorenz W.M., Markus S.H., Bots M.İ., et all. Preduction of Clinical Cardiovackular Events with carotid intima-media thickness // Circulation 2007; 115 (4); 459-67.

Huelth J., Wiklund O., de Feyter P.J., Wendelhog İ. Atherosclerotic changes in the carotid artery bulb as measured by M-mode ultrasound are associated with the exlent of coronary atherosclerosis // Stroke. 1997; 28(6): 1189-94. Dol: htpp: /dx. Doi. Orq / 10, 1161 /01. St. 28.6.

Salonen J.T., Salonen R. Ultrasonographycall assessend carotid morphology and the risk of coronary heat disease // Arterioscler. Tromb 1991;11: p-1245-9.

Vanhoutte P.M. Endotelial disfunction in hipertension // Journale of Hipertension. suppl. 1996. Vol 14. №5. P. 83-93.

Joung-Hoen L., Min-Ho Sh., Sun-Seog K., Hae-Sung N., Kyon-Soo P., et all. Normative and mean carotid intima-media thickness values according to metabolic syndrome in Koreans: The Namwon study // Atherosclerosis. 2014. 234, 230-236.

Jung-Hwan K., Jung Gum R., Jeong-Wan L., Ji Hye K. Gallstones are Associated with intima-media thickness of Common Carotid Arteries in men // Korean J. Fam., 2014, Med. 35- 36.

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Published

31.12.2019

How to Cite

Shiraliyeva, R., Guliyeva, N., Hasanov, X., Aliyev, R., & Aliyeva, D. (2019). Assesment of the Influence of Atoregenic Risk Factors on The Thickness of Intimamedia Complex of The Common Carotid Artery in Patients with Type 2 Diabetes Mellitus. National Journal of Neurology, 18–23. https://doi.org/10.61788/njn.v2i19.02

Issue

2019: No.2 (16)

Section

Original Articles

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