Primary and Recurrent Strokes: Clinical and Pathogenetic Relations

Abstract

Based on the data of clinical and laboratory-instrumental study of 81 patients with recurrent stroke, (including 63 cases after the primary ischemic stroke and 18 cases after the primary hemorrhagic stroke), we compared clinical-pathogenetic correlations between primary and recurrent strokes. A trend towards the localization of a focus of recurrent stroke in the same hemisphere in case of the similar to the primary stroke clinical form and in the other hemisphere in case of changing the clinical form (ischemic to hemorrhagic and vice versa) was found. Among the pathogenetic types of ischemic stroke, lacunar and hemoreologic types were most stable in recurrent stroke compared to the primary one. In other variants, the pathogenesis of recurrent stroke changed more often. The authors concluded that further research in this direction would help to solve issues in prediction of recurrent stroke and improvement of secondary prevention.