Postoperative Cognitive Dysfunction

Authors

  • O.Sh. Eshonov Bukhara State Medical Institute, Bukhara, Uzbekistan
  • U.B. Oltiev Bukhara State Medical Institute, Bukhara, Uzbekistan
  • M.M. Zhamolov Bukhara State Medical Institute, Bukhara, Uzbekistan

DOI:

https://doi.org/10.61788/njn.spec.18.5

Keywords:

early postoperative cognitive dysfunction, ketamine, general anesthesia

Abstract

An evaluation of the incidence of early postoperative cognitive dysfunction (PDCD) in patients after various operations performed under conditions of general anesthesia was implemented. To assess cognitive abilities, the Montreal Cognitive Evaluation Scale (MoCA) and the 10-word test, was used. A study was made of the state of cognitive functions in the postoperative period after various operations under conditions of general anesthesia in 112 patients (40 women and 72 men) with a neurological and psychosomatic history. It was found that general anesthesia causes a decrease in cognitive parameters from 3 to 7 days and within 1-3 months after surgery in 55.3% of patients. The conducted study confirms the high prevalence of cognitive dysfunction in anaesthesiological practice in the postoperative period. The practical significance of the PDCD concept is the possibility of prevention, early diagnosis of cognitive disorders and the initiation of neuroprotective treatment in the postoperative period.

References

Большедворов Р.В., Кичин В.В., Федоров С.А., Лихванцев В.В. Эпидемиология послеоперационных когнитивных расстройств // Анестезия и реанимация. - 2009. - № 3. - С. 20-23.

Давыдов В.В. Нейрмарк М.И. Влияние тотальной внутривенной анестезии с применением кетамина на состояние высших психических функций в послеоперационном периоде// Анестезиология и реаниматология, 2004, №4: с. 37-40.

Неймарк М.И., Давыдов В.В. Состояние высших психических функций у больных, перенесших анестезию с применением дипривана и кетамина // Общая реаниматология, 2005; Т. 1, № 2:. 48-52.

Овезов А.М., Лобов М.А., Пантелеева М.В., Луговой А.В., Мятчин П.С., Гусько И.Е. Коррекция ранних когнитивных нарушений у детей школьного возраста, оперированных в условиях тотальной внутривенной анестезии//Анестезиология и реаниматология, 2012; № 3: С. 1-4.

Шнайдер Н.А. Новый взгляд на проблему послеоперационной когнитивной дисфункции // Острые и неотложные состояния в практике врача, 2008; № 5-6: С. 64-68.

Lobov M., Knyazev A., Ovezov A. et al. Perioperative prevention of early cognitive dysfunction in children. Intensive Care Med. 2010; 36 (Suppl. 2): 276.

Abildstrom H., Rasmussen L.S., Rentowl P. et al. Cognitive dysfunction 1–2 years after non-cardiac surgery in the elderly // Acta Anaesthesiol. Scand., 2000; №44: р.1246-51.

Postoperative cognition disorders in elderly patients. The results of the «International study of postoperative cognitive dysfunction» / Biedler A., Juckenhцfel S., Larsen R. et al. // Anaesthesist. - 1999. - Vol. 48, № 12. - P. 884-895.

Rasmussen L.S., Jonson T., Knipers H.M. et al. Does anesthesia cause postoperative cognitive dysfunction? A randomized study of regional versus general anesthesia in 438 elderly patients // Acta Anesth. Scand. - 2003. - Vol. 47, № 9. - P.1188-1194.

Thomas J., Crosby G., Drummond J. C., Todd M. Anesthetic neurotoxicity: A difficult dragon to slay. Anesth. Analg. 2011; 113 (5): 969-971.

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Published

18.10.2018

How to Cite

Eshonov, O., Oltiev, U., & Zhamolov, M. (2018). Postoperative Cognitive Dysfunction. National Journal of Neurology, 2(14), 39–41. https://doi.org/10.61788/njn.spec.18.5