The Outcomes of Pregnancy in Women with Epilepsy: The Results of a Retrospective Study
DOI:
https://doi.org/10.61788/njn.v2i17.03Keywords:
epilepsy, pregnancy, antiepileptic drugs, delivery outcomeAbstract
A retrospective study of the outcomes of pregnancy and delivery based on the analysis of the case histories of 95 women with epilepsy during 5 years was carried out. A statistically significant prevalence of caesarean section in women with epilepsy in comparison with the control group (p<0.001) was identified. Analysis of the outcomes of delivery showed that epilepsy was an indication for caesarean section as the only factor or in combination with obstetrical indications in 54 (56.8±5.1%) cases. The incidence of premature rupture of membranes was significantly (p<0.001) higher in women with epilepsy, both those who received and did not receive antiepileptic drugs, compared with the control group. A significantly lowered Apgar scores in neonates born to women with epilepsy compared to controls was noted. Stillbirth has been observed in 2 (2.1±1.5%) women with epilepsy. The obtained results showed a very high rate of cesarean section (95.8%) and relatively low rate of practically healthy newborns (47.9%) in women with epilepsy. This indicates the need for more careful monitoring of pregnant women with epilepsy, the correct choice of antiepileptic drugs and their dose, pregnancy planning and prepregnancy counseling.
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