Immunological and Autoimmune Reactivity of Children with Stroke

Authors

  • N.S. Kasimova Department of "Neurology, Child Neurology and Medical Genetic" of Tashkent Pediatric Medical Institute, Tashkent, Uzbekistan
  • Yo.N. Madjidova Department of "Neurology, Child Neurology and Medical Genetic" of Tashkent Pediatric Medical Institute, Tashkent, Uzbekistan
  • D.A. Alidjanova Department of "Neurology, Child Neurology and Medical Genetic" of Tashkent Pediatric Medical Institute, Tashkent, Uzbekistan
  • D.M. Yusupova Department of "Neurology, Child Neurology and Medical Genetic" of Tashkent Pediatric Medical Institute, Tashkent, Uzbekistan

DOI:

https://doi.org/10.61788/njn.v2i16.05

Keywords:

children’s stroke, immunologic reactivity

Abstract

The study was based on data study of immunological parameters in 28 children with stroke in different periods of the disease. Thus, it was found that in children with acute disease there is a violation of the cytokine balance in favor of pro-inflammatory cytokine overproduction and excessive symptoms accompanied by inflammation, which is central to the pathogenesis of this disease. The level of autoantibodies to the vascular endothelium (ANCA) was 3 times higher than the control values, indicating that a pronounced inflammation of the intima of blood vessels. The children in the late recovery period are observed normalization of cytokine status due to lower inflammation of the intimae of blood vessels.

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Published

31.12.2016

How to Cite

Kasimova, N., Madjidova, Y., Alidjanova, D., & Yusupova, D. (2016). Immunological and Autoimmune Reactivity of Children with Stroke. National Journal of Neurology, 30–34. https://doi.org/10.61788/njn.v2i16.05

Issue

2016: No.2 (10)

Section

Original Articles

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