Comparative Evaluation of Non-Motor Displays of The Parkinson's Disease and Vascular Parkinsonism

Abstract

The purpose of the research: To conduct a comparative analysis of the frequency and nature of the non-motor manifestations of Parkinson's disease (PD) and vascular parkinsonism (VP).
Material and Methods. The research was carried out in 153 patients with Parkinson's disease (PD) and 69 patients with vascular parkinsonism (VP). Clinical and neurological studies, assessment of the severity of emotional disorders using g scale HADS, cognitive function was examined by the scale MMSE.
Results. Autonomic disturbances were observed in 2.5 times more likely in patients with PD and 85% in patients with VP, they were observed by us in 30% of patients. Among autonomic dysfunctions in patients with PD, the most frequently observed general hyperhidrosis, voiding, and constipation. . In patients with VP autonomic disorders occurred less often than patients with PD, however, the severity and frequency of occurrence of orthostatic hypotension was higher in VP compared with PD. Among emotional disorders in PD one of the most frequent was a depressive syndrome. It was observed in 58.8% of patients, while in the group with vascular parkinsonism its frequency was 30.4%. Level of depression of HADS in PD was statistically higher than VP patients. Cognitive impairment developed in both groups, approximately at the same percentage of cases; however, the degree of cognitive impairment was higher in the group of patients with VP.