Electrolyte and Gases Composition of Blood in Hypoxic-Ischemic Encephalopathy
DOI:
https://doi.org/10.61788/njn.v1i25.10Keywords:
hypoxic-ischemic encephalopathy, acid-base state, perinatal asphyxia, newbornAbstract
Perinatal asphyxia, which results in hypoxic-ischemic encephalopathy (HIE), causes a number of clinical and biochemical changes that can adversely affect the outcome. Therefore, we set out to study the parameters of the acid-base state of the blood in full-term newborns with HIE who suffered perinatal asphyxia. For this purpose, we studied 120 full-term newborns, including 90 patients with HIE of varying severity who had suffered perinatal asphyxia. The results of the study showed a decrease in the partial pressure of pCO2 and pO2 and the level of blood oxygen saturation (sO2), hypocalcemia, hypoglycemia and a decrease in the concentration of bicarbonate HCO3.
References
Acun, C., Karnati, S., Padiyar, S., Puthuraya, S., et al. Trends of neonatal hypoxic-ischemic encephalopathy prevalence and associated risk factors in the United States, 2010 to 2018 // American journal of obstetrics and gynecology, 2022, 227(5), 751.e1-751.e10. https://doi.org/10.1016/j.ajog.2022.06.002
Ristovska, S., Stomnaroska, O., Danilovski, D. Hypoxic Ischemic Encephalopathy (HIE) in Term and Preterm Infants // Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki), 2022, 43(1), 77-84. https://doi.org/10.2478/prilozi-2022-0013
Greco, P., Nencini, G., Piva, I., Scioscia, M., et al. Pathophysiology of hypoxic-ischemic encephalopathy: a review of the past and a view on the future // Acta neurologica Belgica, 2020, 120(2), 277-288. https://doi.org/10.1007/s13760-020-01308-3
Thakur J, Bhatta NK, Singh RR, Poudel P, et al. Prevalence of electrolyte disturbances in perinatal asphyxia: a prospective study // Ital J Pediatr. 2018 May 21;44(1):56. doi: 10.1186/s13052-018-0496-7.
Acharya A, Swain B, Pradhan S, Jena PK, et al. Clinico-Biochemical Correlation in Birth Asphyxia and Its Effects on Outcome // Cureus. 2020 Nov 9;12(11):e11407. doi: 10.7759/cureus.11407
Ottolini KM, Basu SK, Herrera N, Govindan V, et al. Positive fluid balance is associated with death and severity of brain injury in neonates with hypoxic-ischemic encephalopathy // J Perinatol. 2021 Jun;41(6):1331-1338. doi: 10.1038/s41372-021-00988-w.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 National Association of Neurologists

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.



